Liposome encapsulated Disulfiram inhibits NFκB pathway and targets breast cancer stem cells in vitro and in vivo

Breast cancer stem cells (BCSCs) are pan-resistant to different anticancer agents and responsible for cancer relapse. Disulfiram (DS), an antialcoholism drug, targets CSCs and reverses pan-chemoresistance. The anticancer application of DS is limited by its very short half-life in the bloodstream. Th...

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Hlavní autoři: Liu, Peng, Wang, Zhipeng, Brown, Sarah, Kannappan, Vinodh, Tawari, Patricia Erebi, Jiang, Wenguo, Irache, Juan M., Tang, James Z., Britland, Stephen, Armesilla, Angel L., Darling, John L., Tang, Xing, Wang, Weiguang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202137/
https://ncbi.nlm.nih.gov/pubmed/25277186
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