PP06. HYPOMETHYLATION OF HEXOKINASE 2 IS A FREQUENT EVENT IN GLIOBLASTOMA MULTIFORME

HK2 is highly expressed in several cancers including colon and breast and its role as the rate-limiting step of glycolysis may potentially contribute to tumour growth. Overexpression of HK2 has also been associated with drug resistant phenotypes. Inhibition of HK2 has increased the effectiveness of...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neuro Oncol
Main Authors: Blakeway, Mr Daniel, Karakoula, Dr Katherine, Morris, Dr Mark, Eagles, Mr Lawrence, Rowther, Dr Farjana Begam, Singh, Dr Anushree, Ashton, Mrs Kate, Dawson, Prof Tim, Darling, Prof John, Warr, Prof Tracy
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2017
נושאים:
Abstracts
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358573/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now293.005
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