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PP06. HYPOMETHYLATION OF HEXOKINASE 2 IS A FREQUENT EVENT IN GLIOBLASTOMA MULTIFORME

HK2 is highly expressed in several cancers including colon and breast and its role as the rate-limiting step of glycolysis may potentially contribute to tumour growth. Overexpression of HK2 has also been associated with drug resistant phenotypes. Inhibition of HK2 has increased the effectiveness of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Blakeway, Mr Daniel, Karakoula, Dr Katherine, Morris, Dr Mark, Eagles, Mr Lawrence, Rowther, Dr Farjana Begam, Singh, Dr Anushree, Ashton, Mrs Kate, Dawson, Prof Tim, Darling, Prof John, Warr, Prof Tracy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358573/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now293.005
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