PP06. HYPOMETHYLATION OF HEXOKINASE 2 IS A FREQUENT EVENT IN GLIOBLASTOMA MULTIFORME

HK2 is highly expressed in several cancers including colon and breast and its role as the rate-limiting step of glycolysis may potentially contribute to tumour growth. Overexpression of HK2 has also been associated with drug resistant phenotypes. Inhibition of HK2 has increased the effectiveness of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Blakeway, Mr Daniel, Karakoula, Dr Katherine, Morris, Dr Mark, Eagles, Mr Lawrence, Rowther, Dr Farjana Begam, Singh, Dr Anushree, Ashton, Mrs Kate, Dawson, Prof Tim, Darling, Prof John, Warr, Prof Tracy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358573/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now293.005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados