OP06. Genomic analysis of paired primary and recurrent glioblastoma samples

Primary glioblastoma (GBM) tumours recur following treatment. This is likely due to intratumour heterogeneity (ITH), which reduces the effectiveness of cancer therapies by enabling therapy-driven tumour evolution: Darwinian selection of genotypically and/or phenotypically distinct cells (subclones)...

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Publicat a:Neuro Oncol
Autors principals: Stead, Dr Lucy, Bruns, Dr Alexander, Rippaus, Dr Nora, Morton, Mrs Ruth, Chakrabarty, Dr Arundhati, Ismail, Dr Azzam, King, Dr Henry, Ashton, Mrs Kate, Syed, Mr Khaja, Jenkinson, Mr Michael, Brodbelt, Mr Andrew, Short, Prof Susan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358558/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now292.005
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