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Optimising single cell RNAseq for the analysis of paired primary and recurrent Glioblastoma

Glioblastoma (GBM) brain tumours are notoriously heterogeneous, constituting numerous subpopulations of cells with distinct genotypes and/or phenotypes. This level of heterogeneity is likely to facilitate Darwinian selection of treatment-resistant subpopulations during standard therapy and, thus, co...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Rippaus, Nora, Morton, Ruth, Taylor, Claire, Bruns, Alexander-Francisco, Wurdak, Heiko, Chakrabarty, Aruna, Ismail, Azzam, Short, Susan, Stead, Lucy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791706/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.100
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