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Rho GTPase signaling and role of the Rac1 exchange factor DOCK4 in GBM invasion and vascular growth

INTRODUCTION: The aggressive nature of brain tumours and resistance to therapy is highly influenced by the tumour microenvironment. A key feature of glioblastoma, also used in diagnosis, is the high degree of aberrant vascularity. Rho GTPases are key regulators of blood vessel growth and morphology....

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Bibliografski detalji
Izdano u:Neuro Oncol
Glavni autori: Egnuni, Teklu, Speirs, Valerie, Chakrabarty, Aruna, Wurdak, Heiko, Short, Susan, Mavria, Georgia
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791693/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.077
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