RHO to the DOCK for GDP disembarking: Structural insights into the DOCK GTPase nucleotide exchange factors

The human dedicator of cytokinesis (DOCK) family consists of 11 structurally conserved proteins that serve as atypical RHO guanine nucleotide exchange factors (RHO GEFs). These regulatory proteins act as mediators in numerous cellular cascades that promote cytoskeletal remodeling, playing roles in v...

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Vydáno v:J Biol Chem
Hlavní autoři: Thompson, Andrew P., Bitsina, Christina, Gray, Janine L., von Delft, Frank, Brennan, Paul E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
JBC Reviews
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063744/
https://ncbi.nlm.nih.gov/pubmed/33684443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100521
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