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Rho GTPase signaling and role of the Rac1 exchange factor DOCK4 in GBM invasion and vascular growth
INTRODUCTION: The aggressive nature of brain tumours and resistance to therapy is highly influenced by the tumour microenvironment. A key feature of glioblastoma, also used in diagnosis, is the high degree of aberrant vascularity. Rho GTPases are key regulators of blood vessel growth and morphology....
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5791693/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.077 |
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