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Rho GTPase signaling and role of the Rac1 exchange factor DOCK4 in GBM invasion and vascular growth
INTRODUCTION: The aggressive nature of brain tumours and resistance to therapy is highly influenced by the tumour microenvironment. A key feature of glioblastoma, also used in diagnosis, is the high degree of aberrant vascularity. Rho GTPases are key regulators of blood vessel growth and morphology....
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5791693/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.077 |
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