OP06. Genomic analysis of paired primary and recurrent glioblastoma samples

Primary glioblastoma (GBM) tumours recur following treatment. This is likely due to intratumour heterogeneity (ITH), which reduces the effectiveness of cancer therapies by enabling therapy-driven tumour evolution: Darwinian selection of genotypically and/or phenotypically distinct cells (subclones)...

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發表在:Neuro Oncol
Main Authors: Stead, Dr Lucy, Bruns, Dr Alexander, Rippaus, Dr Nora, Morton, Mrs Ruth, Chakrabarty, Dr Arundhati, Ismail, Dr Azzam, King, Dr Henry, Ashton, Mrs Kate, Syed, Mr Khaja, Jenkinson, Mr Michael, Brodbelt, Mr Andrew, Short, Prof Susan
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358558/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now292.005
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