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Optical control of AMPA receptors using a photoswitchable quinoxaline-2,3-dione antagonist

AMPA receptors respond to the neurotransmitter glutamate and play a critical role in excitatory neurotransmission. They have been implicated in several psychiatric disorders and have rich pharmacology. Antagonists of AMPA receptors have been explored as drugs and one has even reached the clinic. We...

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Bibliografiska uppgifter
I publikationen:Chem Sci
Huvudupphovsmän: Barber, David M., Liu, Shu-An, Gottschling, Kevin, Sumser, Martin, Hollmann, Michael, Trauner, Dirk
Materialtyp: Artigo
Språk:Inglês
Publicerad: Royal Society of Chemistry 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358534/
https://ncbi.nlm.nih.gov/pubmed/28451208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc01621a
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