Optical control of NMDA receptors with a diffusible photoswitch

N-methyl-D-aspartate receptors (NMDARs) play a central role in synaptic plasticity, learning and memory, and are implicated in various neuronal disorders. We synthesized a diffusible photochromic glutamate analogue, azobenzene-triazole-glutamate (ATG), which is specific for NMDARs and functions as a...

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Vydáno v:Nat Commun
Hlavní autoři: Laprell, Laura, Repak, Emilienne, Franckevicius, Vilius, Hartrampf, Felix, Terhag, Jan, Hollmann, Michael, Sumser, Martin, Rebola, Nelson, DiGregorio, David A., Trauner, Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560805/
https://ncbi.nlm.nih.gov/pubmed/26311290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9076
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