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Optical control of AMPA receptors using a photoswitchable quinoxaline-2,3-dione antagonist

AMPA receptors respond to the neurotransmitter glutamate and play a critical role in excitatory neurotransmission. They have been implicated in several psychiatric disorders and have rich pharmacology. Antagonists of AMPA receptors have been explored as drugs and one has even reached the clinic. We...

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Vydáno v:Chem Sci
Hlavní autoři: Barber, David M., Liu, Shu-An, Gottschling, Kevin, Sumser, Martin, Hollmann, Michael, Trauner, Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358534/
https://ncbi.nlm.nih.gov/pubmed/28451208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc01621a
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