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In vitro TNF blockade enhances ex vivo expansion of regulatory T cells in patients with immune thrombocytopenia

Tumour necrosis factor-α (TNF) is an inflammatory cytokine that is elevated in a number of autoimmune diseases including immune thrombocytopenia (ITP), a bleeding disorder characterized by low platelet counts. In vitro TNF blockade increases expansion of the regulatory T cell (Treg) IKZF2 (also term...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Zhong, Hui, Bussel, James, Yazdanbakhsh, Karina
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358513/
https://ncbi.nlm.nih.gov/pubmed/25252160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13126
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