CD16(+) monocytes control T-cell subset development in immune thrombocytopenia

Immune thrombocytopenia (ITP) results from decreased platelet production and accelerated platelet destruction. Impaired CD4(+) regulatory T-cell (Treg) compartment and skewed Th1 and possibly Th17 responses have been described in ITP patients. The trigger for aberrant T-cell polarization remains unk...

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Autores principales: Zhong, Hui, Bao, Weili, Li, Xiaojuan, Miller, Allison, Seery, Caroline, Haq, Naznin, Bussel, James, Yazdanbakhsh, Karina
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476543/
https://ncbi.nlm.nih.gov/pubmed/22915651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-434605
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