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CD16(+) monocytes control T-cell subset development in immune thrombocytopenia
Immune thrombocytopenia (ITP) results from decreased platelet production and accelerated platelet destruction. Impaired CD4(+) regulatory T-cell (Treg) compartment and skewed Th1 and possibly Th17 responses have been described in ITP patients. The trigger for aberrant T-cell polarization remains unk...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3476543/ https://ncbi.nlm.nih.gov/pubmed/22915651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-434605 |
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