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Differential control of Helios(+/−) Treg development by monocyte subsets through disparate inflammatory cytokines

Foxp3(+) regulatory T cells (Tregs) play a pivotal role in control of autoimmunity and pathological immune responses. Helios, the Ikarus family transcription factor, binds to the Foxp3 promoter, stabilizing its expression, and is expressed in 70% of peripheral Tregs of healthy individuals. This freq...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zhong, Hui, Yazdanbakhsh, Karina
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612859/
https://ncbi.nlm.nih.gov/pubmed/23365462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-469122
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