Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents

Immune thrombocytopenia (ITP) is an autoantibody-mediated bleeding disorder with both accelerated platelet destruction and impaired platelet production. We and others have described impaired regulatory CD4(+)CD25(hi) T cells (Treg) numbers and/or suppressive function in ITP patients. Clinical trials...

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Detalhes bibliográficos
Main Authors: Bao, Weili, Bussel, James B., Heck, Susanne, He, Wu, Karpoff, Marissa, Boulad, Nayla, Yazdanbakhsh, Karina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996119/
https://ncbi.nlm.nih.gov/pubmed/20688957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-281717
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