Retinol-binding protein 7 is an endothelium-specific PPARγ cofactor mediating an antioxidant response through adiponectin

Impaired PPARγ activity in endothelial cells causes oxidative stress and endothelial dysfunction which causes a predisposition to hypertension, but the identity of key PPARγ target genes that protect the endothelium remain unclear. Retinol-binding protein 7 (RBP7) is a PPARγ target gene that is esse...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Hu, Chunyan, Keen, Henry L., Lu, Ko-Ting, Liu, Xuebo, Wu, Jing, Davis, Deborah R., Ibeawuchi, Stella-Rita C., Vogel, Silke, Quelle, Frederick W., Sigmund, Curt D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358481/
https://ncbi.nlm.nih.gov/pubmed/28352663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91738
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