Interference with PPARγ in endothelium accelerates angiotensin II-induced endothelial dysfunction

The ligand activated nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) in the endothelium regulates vascular function and blood pressure (BP). We previously reported that transgenic mice (E-V290M) with selectively targeted endothelial-specific expression of dominant negative PPAR...

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Publicat a:Physiol Genomics
Autors principals: Hu, Chunyan, Lu, Ko-Ting, Mukohda, Masashi, Davis, Deborah R., Faraci, Frank M., Sigmund, Curt D.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
Matèries:
Genomic and "Polyomic" Studies of Cardiovascular and Inflammatory Diseases
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729699/
https://ncbi.nlm.nih.gov/pubmed/26534936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00087.2015
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