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Genetic Interference with Endothelial PPARγ Augments Effects of Angiotensin II While Impairing Responses to Angiotensin 1-7

Pharmacological activation of peroxisome proliferator-activated receptor-γ (PPARγ) protects the vasculature. Much less is known regarding the cell specific impact of PPARγ when driven by endogenous ligands. Recently, we found that endothelial PPARγ protects against angiotensin II (Ang II)-induced en...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: De Silva, T. Michael, Hu, Chunyan, Kinzenbaw, Dale A., Modrick, Mary L, Sigmund, Curt D., Faraci, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552422/
https://ncbi.nlm.nih.gov/pubmed/28674038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09358
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