Wird geladen...
PPARγ: No SirT, No Service
A novel mechanism has been defined for controlling PPARγn activity in response to thiazolidinedione ligands, in which deacetylation of PPARγ by SirT1 remodels the transcriptional complex. This change favors expression of genes associated with increased energy utilization and insulin sensitization in...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580855/ https://ncbi.nlm.nih.gov/pubmed/23371897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.300870 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|