Synergy of cAMP and calcium signaling pathways in CFTR regulation

Cystic fibrosis results from mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel, leading to defective apical chloride transport. Patients also experience overactivation of inflammatory processes, including increased calcium signaling. Many investigations hav...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bozoky, Zoltan, Ahmadi, Saumel, Milman, Tal, Kim, Tae Hun, Du, Kai, Di Paola, Michelle, Pasyk, Stan, Pekhletski, Roman, Keller, Jacob P., Bear, Christine E., Forman-Kay, Julie D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358358/
https://ncbi.nlm.nih.gov/pubmed/28242698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613546114
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