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Structural changes of CFTR R region upon phosphorylation: a plastic platform for intramolecular and intermolecular interactions
Chloride channel gating and trafficking of the cystic fibrosis transmembrane conductance regulator (CFTR) are regulated by phosphorylation. Intrinsically disordered segments of the protein are responsible for phospho‐regulation, particularly the regulatory (R) region that is a target for several kin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4160016/ https://ncbi.nlm.nih.gov/pubmed/23826884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12422 |
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