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Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: A strategy to promote cartilage repair

Osteoarthritis is a degenerative joint disease characterized by a progressive loss of articular cartilage components, mainly proteoglycans (PGs), leading to destruction of the tissue. We investigate a therapeutic strategy based on stimulation of PG synthesis by gene transfer of the glycosaminoglycan...

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Autors principals: Venkatesan, N., Barré, L., Benani, A., Netter, P., Magdalou, J., Fournel-Gigleux, S., Ouzzine, M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC535800/
https://ncbi.nlm.nih.gov/pubmed/15601778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404504102
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