Xylosyltransferase-I Regulates Glycosaminoglycan Synthesis during the Pathogenic Process of Human Osteoarthritis

Loss of glycosaminoglycan (GAG) chains of proteoglycans (PGs) is an early event of osteoarthritis (OA) resulting in cartilage degradation that has been previously demonstrated in both huma and experimental OA models. However, the mechanism of GAG loss and the role of xylosyltransferase-I (XT-I) that...

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Main Authors: Venkatesan, Narayanan, Barré, Lydia, Bourhim, Mustapha, Magdalou, Jacques, Mainard, Didier, Netter, Patrick, Fournel-Gigleux, Sylvie, Ouzzine, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316535/
https://ncbi.nlm.nih.gov/pubmed/22479506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034020
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