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The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication
UDP-glucuronosyltransferases (UGTs) form a multigenic family of membrane-bound enzymes expressed in various tissues, including brain. They catalyze the formation of β-D-glucuronides from structurally unrelated substances (drugs, other xenobiotics, as well as endogenous compounds) by the linkage of g...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4211562/ https://ncbi.nlm.nih.gov/pubmed/25389387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00349 |
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