Phylogenetic and mutational analyses reveal key residues for UDP-glucuronic acid binding and activity of β1,3-glucuronosyltransferase I (GlcAT-I)

The β1,3-glucuronosyltransferases are responsible for the completion of the protein–glycosaminoglycan linkage region of proteoglycans and of the HNK1 epitope of glycoproteins and glycolipids by transferring glucuronic acid from UDP-α-D-glucuronic acid (UDP-GlcA) onto a terminal galactose residue. He...

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Main Authors: Fondeur-Gelinotte, Magali, Lattard, Virginie, Oriol, Rafael, Mollicone, Rosella, Jacquinet, Jean-Claude, Mulliert, Guillermo, Gulberti, Sandrine, Netter, Patrick, Magdalou, Jacques, Ouzzine, Mohamed, Fournel-Gigleux, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242556/
https://ncbi.nlm.nih.gov/pubmed/16815917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062089106
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