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Phylogenetic and mutational analyses reveal key residues for UDP-glucuronic acid binding and activity of β1,3-glucuronosyltransferase I (GlcAT-I)
The β1,3-glucuronosyltransferases are responsible for the completion of the protein–glycosaminoglycan linkage region of proteoglycans and of the HNK1 epitope of glycoproteins and glycolipids by transferring glucuronic acid from UDP-α-D-glucuronic acid (UDP-GlcA) onto a terminal galactose residue. He...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242556/ https://ncbi.nlm.nih.gov/pubmed/16815917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062089106 |
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