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Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders
Sirtuins (SIRT1–SIRT7) are unique histone deacetylases (HDACs) whose activity depends on NAD(+) levels and thus on the cellular metabolic status. SIRTs regulate energy metabolism and mitochondrial function. They orchestrate the stress response and damage repair. Through these functions sirtuins modu...
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| Publicado no: | Neurochem Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357501/ https://ncbi.nlm.nih.gov/pubmed/27882448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-016-2110-y |
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