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Fingolimod Affects Transcription of Genes Encoding Enzymes of Ceramide Metabolism in Animal Model of Alzheimer’s Disease

The imbalance in sphingolipid signaling may be critically linked to the upstream events in the neurodegenerative cascade of Alzheimer’s disease (AD). We analyzed the influence of mutant (V717I) amyloid β precursor protein (AβPP) transgene on sphingolipid metabolism enzymes in mouse hippocampus. At 3...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Jęśko, Henryk, Wencel, Przemysław L., Wójtowicz, Sylwia, Strosznajder, Joanna, Lukiw, Walter J., Strosznajder, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253528/
https://ncbi.nlm.nih.gov/pubmed/32356173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-01908-3
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