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Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho
Fibrosis is an exaggerated form of tissue repair that occurs with serious damage or repetitive injury and ultimately leads to organ failure due to the excessive scarring. Increased calcium ion entry through the TRPC6 channel has been associated with the pathogenesis of heart and glomerular diseases,...
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| Publié dans: | Kidney Int |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357448/ https://ncbi.nlm.nih.gov/pubmed/27979597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.09.039 |
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