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Opposing effects on the cell cycle of T lymphocytes by Fbxo7 via Cdk6 and p27

G(1) phase cell cycle proteins, such as cyclin-dependent kinase 6 (Cdk6) and its activating partners, the D-type cyclins, are important regulators of T-cell development and function. An F-box protein, called F-box only protein 7 (Fbxo7), acts as a cell cycle regulator by enhancing cyclin D-Cdk6 comp...

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Publicat a:Cell Mol Life Sci
Autors principals: Patel, Shachi P., Randle, Suzanne J., Gibbs, Sarah, Cooke, Anne, Laman, Heike
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357273/
https://ncbi.nlm.nih.gov/pubmed/27915416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-016-2427-3
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