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Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6
D cyclins (D1, D2 and D3) and their catalytic subunits (cyclin-dependent kinases cdk4 and cdk6) have a facilitating, but nonessential, role in cell cycle entry. Tissue-specific functions for D-type cyclins and cdks have been reported; however, the biochemical properties of these kinases are indistin...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201355/ https://ncbi.nlm.nih.gov/pubmed/16096642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600775 |
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