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Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins

F-box proteins (FBPs) are substrate-recruiting subunits of Skp1-cullin1-FBP (SCF)-type E3 ubiquitin ligases. To date, 69 FBPs have been identified in humans, but ubiquitinated substrates have only been identified for a few, with the majority of FBPs remaining ‘orphans’. In recent years, a growing bo...

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Hlavní autoři: Nelson, David E., Randle, Suzanne J., Laman, Heike
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814724/
https://ncbi.nlm.nih.gov/pubmed/24107298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.130131
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