Loading...

Expression of Fbxo7 in Haematopoietic Progenitor Cells Cooperates with p53 Loss to Promote Lymphomagenesis

Fbxo7 is an unusual F box protein that augments D-type cyclin complex formation with Cdk6, but not Cdk4 or Cdk2, and its over-expression has been demonstrated to transform immortalised fibroblasts in a Cdk6-dependent manner. Here we present new evidence in vitro and in vivo on the oncogenic potentia...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lomonosov, Mikhail, Meziane, El Kahina, Ye, Hongtao, Nelson, David E., Randle, Suzanne J., Laman, Heike
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117880/
https://ncbi.nlm.nih.gov/pubmed/21695055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021165
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!