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Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6

D cyclins (D1, D2 and D3) and their catalytic subunits (cyclin-dependent kinases cdk4 and cdk6) have a facilitating, but nonessential, role in cell cycle entry. Tissue-specific functions for D-type cyclins and cdks have been reported; however, the biochemical properties of these kinases are indistin...

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Autors principals: Laman, Heike, Funes, Juan M, Ye, Hongtao, Henderson, Stephen, Galinanes-Garcia, Laura, Hara, Eiji, Knowles, Phillip, McDonald, Neil, Boshoff, Chris
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201355/
https://ncbi.nlm.nih.gov/pubmed/16096642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600775
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