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Extensive phosphorylation of Smoothened in Hedgehog pathway activation

The transmembrane protein Smoothened (Smo) is activated in response to the extracellular protein signal, Hedgehog (Hh), and transmits this state of pathway activity into the cell. Previous studies in Drosophila have correlated pathway activation with Smo accumulation and increased phosphorylation. U...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, Chi, Williams, Elizabeth H., Guo, Yurong, Lum, Lawrence, Beachy, Philip A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC535705/
https://ncbi.nlm.nih.gov/pubmed/15598741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408093101
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