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Extensive phosphorylation of Smoothened in Hedgehog pathway activation
The transmembrane protein Smoothened (Smo) is activated in response to the extracellular protein signal, Hedgehog (Hh), and transmits this state of pathway activity into the cell. Previous studies in Drosophila have correlated pathway activation with Smo accumulation and increased phosphorylation. U...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC535705/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15598741/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408093101 |
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