Inhibition of androgen receptor by decoy molecules delays progression to castration-recurrent prostate cancer

Androgen receptor (AR) is a member of the steroid receptor family and a therapeutic target for all stages of prostate cancer. AR is activated by ligand binding within its C-terminus ligand-binding domain (LBD). Here we show that overexpression of the AR NTD to generate decoy molecules inhibited both...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Myung, Jae-Kyung, Wang, Gang, Chiu, Helen H. L., Wang, Jun, Mawji, Nasrin R., Sadar, Marianne D.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357013/
https://ncbi.nlm.nih.gov/pubmed/28306720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174134
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items