Potentiation of the anticancer effects of everolimus using a dual mTORC1/2 inhibitor in hepatocellular carcinoma cells

There is lots of evidence to support the critical involvement of mTOR signaling in the carcinogenesis of hepatocellular carcinoma (HCC). However, it has not been determined how the roles of individual mTORC1 and mTORC2 inhibitors played in the HCC therapeutics. We thus compared the effects of everol...

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Vydáno v:Oncotarget
Hlavní autoři: Kim, Jong-Ok, Kim, Kee-Hwan, Song, In Sang, Cheon, Kwang-Sik, Kim, Ok-Hee, Lee, Sang Chul, Lee, Sang Kuon, Kim, Say-June
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356853/
https://ncbi.nlm.nih.gov/pubmed/27935857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13808
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