Potentiation of the anticancer effects of everolimus using a dual mTORC1/2 inhibitor in hepatocellular carcinoma cells

There is lots of evidence to support the critical involvement of mTOR signaling in the carcinogenesis of hepatocellular carcinoma (HCC). However, it has not been determined how the roles of individual mTORC1 and mTORC2 inhibitors played in the HCC therapeutics. We thus compared the effects of everol...

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Опубликовано в: :Oncotarget
Главные авторы: Kim, Jong-Ok, Kim, Kee-Hwan, Song, In Sang, Cheon, Kwang-Sik, Kim, Ok-Hee, Lee, Sang Chul, Lee, Sang Kuon, Kim, Say-June
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356853/
https://ncbi.nlm.nih.gov/pubmed/27935857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13808
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