Potentiation of the anticancer effects of everolimus using a dual mTORC1/2 inhibitor in hepatocellular carcinoma cells

There is lots of evidence to support the critical involvement of mTOR signaling in the carcinogenesis of hepatocellular carcinoma (HCC). However, it has not been determined how the roles of individual mTORC1 and mTORC2 inhibitors played in the HCC therapeutics. We thus compared the effects of everol...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Jong-Ok, Kim, Kee-Hwan, Song, In Sang, Cheon, Kwang-Sik, Kim, Ok-Hee, Lee, Sang Chul, Lee, Sang Kuon, Kim, Say-June
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356853/
https://ncbi.nlm.nih.gov/pubmed/27935857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13808
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