Dramatic antitumor effects of the dual mTORC1 and mTORC2 inhibitor AZD2014 in hepatocellular carcinoma

The mammalian target of rapamycin (mTOR) has emerged as a critical effector in cell growth, proliferation, survival, angiogenesis, and autophagy through direct interaction with mTORC1 (mTOR complex 1) and mTORC2 (mTOR complex 2). The mTOR axis is aberrantly activated in about 50% of human hepatocell...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Am J Cancer Res
Autors principals: Liao, Hui, Huang, Yu, Guo, Botang, Liang, Bo, Liu, Xincheng, Ou, Huohui, Jiang, Chenglong, Li, Xianghong, Yang, Dinghua
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2014
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300717/
https://ncbi.nlm.nih.gov/pubmed/25628925
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars