USP19 deubiquitinates HDAC1/2 to regulate DNA damage repair and control chromosomal stability

Excessive accumulation of DNA damage will generate chromosome stress, leading to various chromosome abnormalities such as chromatin bridge and result in genomic instability. Orchestra procession and regulation of DNA damage repair are vital for keeping genome stability. Despite of the key role of HD...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wu, Min, Tu, Hai-qing, Chang, Yan, Tan, Bo, Wang, Guang, Zhou, Jie, Wang, Li, Mu, Rui, Zhang, Wei-na
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356792/
https://ncbi.nlm.nih.gov/pubmed/27517492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11116
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