The antiangiogenic effects of polyisoprenylated cysteinyl amide inhibitors in HUVEC, chick embryo and zebrafish is dependent on the polyisoprenyl moiety

Angiogenesis is essential for solid tumor growth, therapeutic resistance and metastasis, the latest accounting for 90% of cancer deaths. Although angiogenesis is essential for the malignant transformations in solid tumors and therefore is an attractive target, few drugs are available that block tumo...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nkembo, Augustine T., Ntantie, Elizabeth, Salako, Olufisayo O., Amissah, Felix, Poku, Rosemary A., Latinwo, Lekan M., Lamango, Nazarius S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356549/
https://ncbi.nlm.nih.gov/pubmed/27626690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11908
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