Polyisoprenylated cysteinyl amide inhibitors induce caspase 3/7- and 8-mediated apoptosis and inhibit migration and invasion of metastatic prostate cancer cells

Metastatic castration-resistant prostate cancer (mCRPC) is the most aggressive and deadly form of prostate cancer. It is characterized by the overexpression of epidermal growth factor receptors whose signals are mediated by small monomeric G proteins of the Ras superfamily. These require polyisopren...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Poku, Rosemary A, Salako, Olufisayo O, Amissah, Felix, Nkembo, Augustine T, Ntantie, Elizabeth, Lamango, Nazarius S
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523032/
https://ncbi.nlm.nih.gov/pubmed/28744401
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