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Polyisoprenylated cysteinyl amide inhibitors induce caspase 3/7- and 8-mediated apoptosis and inhibit migration and invasion of metastatic prostate cancer cells

Metastatic castration-resistant prostate cancer (mCRPC) is the most aggressive and deadly form of prostate cancer. It is characterized by the overexpression of epidermal growth factor receptors whose signals are mediated by small monomeric G proteins of the Ras superfamily. These require polyisopren...

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Detalles Bibliográficos
Publicado en:Am J Cancer Res
Main Authors: Poku, Rosemary A, Salako, Olufisayo O, Amissah, Felix, Nkembo, Augustine T, Ntantie, Elizabeth, Lamango, Nazarius S
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523032/
https://ncbi.nlm.nih.gov/pubmed/28744401
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