Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1α/PKM2 axis in glioblastoma cells

The human cytomegalovirus (HCMV) encoded chemokine receptor US28 promotes tumorigenesis through activation of various proliferative and angiogenic signaling pathways. Upon infection, US28 displays constitutive activity and signals in a G protein-dependent manner, hijacking the host's cellular m...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: de Wit, Raymond H., Mujić-Delić, Azra, van Senten, Jeffrey R., Fraile-Ramos, Alberto, Siderius, Marco, Smit, Martine J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356532/
https://ncbi.nlm.nih.gov/pubmed/27602585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11817
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