Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1α/PKM2 axis in glioblastoma cells

The human cytomegalovirus (HCMV) encoded chemokine receptor US28 promotes tumorigenesis through activation of various proliferative and angiogenic signaling pathways. Upon infection, US28 displays constitutive activity and signals in a G protein-dependent manner, hijacking the host's cellular m...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: de Wit, Raymond H., Mujić-Delić, Azra, van Senten, Jeffrey R., Fraile-Ramos, Alberto, Siderius, Marco, Smit, Martine J.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356532/
https://ncbi.nlm.nih.gov/pubmed/27602585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11817
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