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DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas

BACKGROUND: Syncytin-1 and 2, human fusogenic glycoproteins encoded by the env genes of the endogenous retroviral loci ERVWE1 and ERVFRDE1, respectively, contribute to the differentiation of multinucleated syncytiotrophoblast in chorionic villi. In non-trophoblastic cells, however, the expression of...

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Bibliografiska uppgifter
I publikationen:Retrovirology
Huvudupphovsmän: Benešová, Martina, Trejbalová, Kateřina, Kovářová, Denisa, Vernerová, Zdenka, Hron, Tomáš, Kučerová, Dana, Hejnar, Jiří
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356313/
https://ncbi.nlm.nih.gov/pubmed/28302141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0342-9
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