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DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas

BACKGROUND: Syncytin-1 and 2, human fusogenic glycoproteins encoded by the env genes of the endogenous retroviral loci ERVWE1 and ERVFRDE1, respectively, contribute to the differentiation of multinucleated syncytiotrophoblast in chorionic villi. In non-trophoblastic cells, however, the expression of...

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Bibliografski detalji
Izdano u:Retrovirology
Glavni autori: Benešová, Martina, Trejbalová, Kateřina, Kovářová, Denisa, Vernerová, Zdenka, Hron, Tomáš, Kučerová, Dana, Hejnar, Jiří
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356313/
https://ncbi.nlm.nih.gov/pubmed/28302141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0342-9
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