DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas

BACKGROUND: Syncytin-1 and 2, human fusogenic glycoproteins encoded by the env genes of the endogenous retroviral loci ERVWE1 and ERVFRDE1, respectively, contribute to the differentiation of multinucleated syncytiotrophoblast in chorionic villi. In non-trophoblastic cells, however, the expression of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Retrovirology
Prif Awduron: Benešová, Martina, Trejbalová, Kateřina, Kovářová, Denisa, Vernerová, Zdenka, Hron, Tomáš, Kučerová, Dana, Hejnar, Jiří
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356313/
https://ncbi.nlm.nih.gov/pubmed/28302141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0342-9
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