Epigenetic regulation of transcription and splicing of syncytins, fusogenic glycoproteins of retroviral origin

Syncytin-1 and -2, human fusogenic glycoproteins encoded by the env genes of the endogenous retroviral loci ERVWE1 and ERVFRDE1, respectively, contribute to the differentiation of multinucleated syncytiotrophoblast in chorionic villi. In non-trophoblastic cells, however, the expression of syncytins...

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Autores principales: Trejbalová, Kateřina, Blažková, Jana, Matoušková, Magda, Kučerová, Dana, Pecnová, Lubomíra, Vernerová, Zdenka, Heráček, Jiří, Hirsch, Ivan, Hejnar, Jiří
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203578/
https://ncbi.nlm.nih.gov/pubmed/21771862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr562
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