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DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas

BACKGROUND: Syncytin-1 and 2, human fusogenic glycoproteins encoded by the env genes of the endogenous retroviral loci ERVWE1 and ERVFRDE1, respectively, contribute to the differentiation of multinucleated syncytiotrophoblast in chorionic villi. In non-trophoblastic cells, however, the expression of...

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Dades bibliogràfiques
Publicat a:Retrovirology
Autors principals: Benešová, Martina, Trejbalová, Kateřina, Kovářová, Denisa, Vernerová, Zdenka, Hron, Tomáš, Kučerová, Dana, Hejnar, Jiří
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356313/
https://ncbi.nlm.nih.gov/pubmed/28302141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0342-9
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